A Complete Guide About Parkinson Disease

Parkinson's disease (PD) is a progressive degenerative disease that has direct effects on nerve cells in the interior of the brain called the basal ganglia and the substance nigra. The nerve cells in the substance Nigra create the neurotransmitter dopamine and are accountable for sending messages that plan and manage body movements. 

When 80% of dopamine is gone, Parkinson's disease symptoms such as tremors, slowness of movement, stiffness, and balance problems appear. It is also said that paraquat is also responsible to cause Parkinson's disease. People who have developed Parkinson's disease after exposure to paraquat are eligible to seek compensation for the loss through filing paraquat Parkinson's lawsuits. If you are also looking to file a lawsuit then you can also 'hop over to this link'.

Parkinson's Disease

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The effects of dopamine counteract another neurotransmitter called acetylcholine. In Parkinson's, the nerve cells that produce dopamine die. Parkinson's symptoms of tremor and stiffness occur when nerve cells become active and there isn't enough dopamine to carry messages. High levels of glutamate, another neurotransmitter, also occur in Parkinson's disease as the body tries to make up for the lack of dopamine.

What are the symptoms?

Symptoms of PD vary from person to person, as does the level of development. A person with Parkinson's disease may experience some of these more common "trademark" symptoms:

  • Bradykinesia
  • Resting tremor
  • Stiffness
  • Postural instability

Other symptoms that may or may not appear:

  • Freeze or paste
  • Touching walking or pulling feet
  • Bending Posture
  • Small and narrow handwriting
  • Difficulty sleeping, insomnia
  • Apathy, depression
  • Decreased volume or shaking while talking
  • Difficulty swallowing
  • Constipation
  • Cognitive impairment